Endocrine Abstracts

Introduction: Sarcoidosis is a multisystem granulomatous disorder. It commonly causes mild hypercalcemia in up to 10–20% of the cases and renal involvement can be a feature. Presentation with severe symptomatic hypercalcaemia (>3.5 mmol/l) and acute kidney injury is rare. We present an interesting case.Case: A 58 year old female was referred to the emergency department by her general practitioner with a one month history of polyuria, generalised wea...

Introduction: Idiopathic hypogonadotrophic hypogonadism (IHH) with normal sense of smell is a complex and rare disease entity characterised by insufficient gonadotropin releasing hormone (GnRH) neuronal action on an intact hypothalamo–pituitary–gonadal axis. IHH has an incidence of 1–10 in 100 000 live births with a variable mode of inheritance and five-fold male predominance. Gene mutations have been discovered of which 10–40% of the familial cases are due...